Full Professor in Biochemistry
Bert Poolman was trained in bioenergetics and microbiology and is now active in biochemistry and biophysics. Central questions in his research are:
(i) how do molecules permeate biological membranes?
(ii) how can one control the volume and physicochemistry of the cell?
(iii) what tasks should a living cell minimally perform and how this can be accomplished with a minimal set of components.
Poolman has a track record in vectorial biochemistry, including membrane transport and cell volume regulation as well as the development of innovative technologies in membrane biology. He has advanced the field of ATP-binding cassette (ABC) and secondary active transporters by combining functional and structural studies. His main current research areas include:
(i) Bacterial cell-volume regulation: Elucidation of the homeostatic mechanisms that control the physicochemistry of the cell.
(ii) Building of synthetic cells: Construction of functional far-from-equilibrium systems for metabolic energy conservation and development of cell volume regulatory networks.
(iii) Traffic of membrane proteins: Understanding of the targeted delivery, localization and energetics of nutrient transporters in the plasma membrane of yeast.
List of publications on Pubmed
E-mail: b.poolman at rug.nl (Please replace at with @)
Telephone RUG: +31 50 363 4190
Room number: 5116-0143